Feline panleukopenia is a highly contagious, often fatal, viral disease of cats that is seen worldwide. Kittens are affected most severely. The causative parvovirus. Feline Panleukopenia virus (FPV), also commonly referred to as feline distemper, is a highly contagious and life-threatening viral disease in cats. Learn more. Feline panleukopenia virus is highly contagious. The virus may be acquired by direct contact with infected cats or via fomites (bedding, food dishes); flies and.

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False-negative results are common. Elsevier – Health Sciences Division. However, it is not intended to be used as a substitute for going to the vet. Inhibitory effects of recombinant feline interferon on the replication of feline enteropathogenic viruses in vitro. Feline parvovirus infection is probably the greatest major disease threat to any rescue facility and infection carries panleukopneia very high mortality rate, particularly in unvaccinated kittens.

Important The information provided here has been put together by experts in feline health, behaviour and welfare. June 10—13,abstract It causes a decrease in the cat’s white blood panleukopenithus compromising its immune system. Feline parvovirus is spread by direct faecal-oral contact, and indirectly following contamination of the environment or objects eg, on food dishes, grooming equipment, bedding, floors, clothing viurs hands.

The virus causes severe damage to the lining of the intestine and also travels via the blood to the bone marrow and lymph glands.

Feline infectious enteritis (parvovirus, panleukopenia virus) | International Cat Care

Treatment involves whole blood transfusion to improve pancytopenia, intravenous fluids as panleuoopenia cats are dehydrated, injections of vitamins A, B, and C, IV antibiotics to prevent septicemiawhich develops in most cats with feline panleukopenia if antibiotics are not used, and hospitalization.

Even cats kept indoors can be infected since the virus is so stable that it can be transmitted on fomites. Disseminated intravascular coagulation may also occur, and is often fatal.


However, FPV kills both erythroid and myeloid colony progenitors in in vitro bone marrow cultures, and it has been suggested that virus replication in the myeloid cells in vivo could lead to the reduced neutrophil levels seen after FPV infection of cats.

Cat diseases Animal virology.

Affected cats may sit for hours at their water bowl, although they may not drink much. Once contracted, it is highly contagious and can be fatal to the affected cat.

This is why administering modified live feline panleukopenia vaccine during pregnancy is discouraged. Kittens may then be born with a condition known as cerebellar hypoplasia lack of development of the cerebellum, a part of the brain needed for fine coordination of movement. Feline panleukopenia virus FPV and canine parvovirus CPV are autonomous parvoviruses which infect cats or dogs, respectively. Control Feline parvovirus is much better prevented than treated.

Modified live vaccines should not be used in pregnant queens or cats that are immunosuppressed and, in such cases, inactivated killed ffline are recommended.

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A cat eradication program was set up and a few cats were intentionally infected with the panleukopenia virus, which reduced the number of cats to about by The viruses have a broad tropism for mitotically active cells. Control of the spread of FPV relies on both vaccination and good management practice, including disinfection with appropriate disinfectants and use of isolation procedures.

Highly effective vaccines are available and all cats and kittens should be vaccinated including indoor-only cats.

This may also happen in very young geline less than 4 weeks of age infected with FPV as the cerebellum is still developing at that age. Starting from the first five domestic panleukooenia introduced on the island onthere were about 3, cats infeeding on the burrowing petrels instead of the mice, threatening to drive the birds to extinction.


Some cats may die before even showing signs of gastroenteritis. Common diseases of companion animals 3rd ed. Please help improve this article by adding citations to reliable sources. Treatment of canine parvoviral enteritis with interferon-omega in a placebo-controlled field trial.

Feline panleukopenia – Wikipedia

Where possible, one or two people who do not handle any other cats should be assigned as nurses. May Learn how and when to remove this template message. A cat diagnosed with FPV should be first of all kept in isolation.

ABCD guidelines on prevention and management.

Pathogenesis of feline panleukopenia virus and canine parvovirus.

Useful links Vaccinating your cat. Feline panleukopenia requires aggressive treatment if the cat is to survive, as this disease can kill cats in less than 24 hours. From Wikipedia, the free encyclopedia. Pregnant panleu,openia infected with parvovirus, the virus can spread to the unborn kittens where it can interfere with the developing brain.

Differential diagnoses include other causes of profound depression, leukopenia, and GI signs. This results in profuse and usually virux diarrhea, severe dehydration, malnutrition, anemiaand often death.

Like, Follow and Pin us to stay up to date with our work. Am J Vet Res; The virus primarily attacks the lining of the gastrointestinal tractcausing internal ulceration and, ultimately, total sloughing of the intestinal epithelium.

Retrieved 26 May Because of the serious disease and ubiquity of the virus vaccination is recommended for every cat. Hyponatremia and other electrolyte disturbances are also quite common, as is hypotensionhyperpyrexia or, late in the disease, hypothermia.