Este fenómeno es conocido como efecto Jod-Basedow. El tratamiento con propiltiouracilo en dosis decrecientes consiguió un estado eutiroideo y mejoró la . Efectos de las hormomas tiroideas en el corazón. Visits . por el efecto de Wolff- Chaikoff, además de hipertiroidismo (mediado por el efecto de Jod-Basedow. de hipertiroidismo (mediado por el efecto de Jod-Basedow. En ambos casos, la causa subyacente es por la alta concentración de yodo en este medicamento.

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Blood sugar regulation Calcium metabolism. Overall, hyperthyroidism is characterized by an increase in resting heart rate, blood volume, stroke volume, myocardial contractility, and ejection fraction. Abstract Exposure to excessive amounts of efectoo blocks the activity of the enzyme thyroid peroxidase TPOa phenomenon known as Wolf-Chaikoff effect.

Med Clin North Am ;75 1: Archives of Internal Medicine ; 2: Universidad Tecnolica de Pereira, Risaralda. CiteScore measures average citations received per document published. Blood sugar regulation Calcium metabolism.

This phenomenon is thus vasedow hyperthyroidismtypically presenting in a patient with endemic goiter due to iodine deficiencywho relocate to an iodine-abundant geographical area. Pharmacology for Women’s Health. On the other hand, when thyrocites have low iodine levels and are exposed to a high iodine concentration, they increase significantly their production of thyroid hormone thus leading to hyperthyroidism, a phenomenon known as Jod-Basedow effect.

Retrieved from ” https: Lancet ; In larger amounts [potassium iodide] acts immediately to block further uptake of iodide basfdow several means, particularly by saturating the iodide transport mechanisms of the thyroid, by inhibiting the intrathyroidal organification of iodide, and by simple dilution.


However, unlike the Wolff-Chaikoff effectthe Jod-Basedow effect does not occur in persons with normal thyroid glands, as thyroid hormone synthesis and release in normal persons is controlled by pituitary TSH secretion which does not allow hyperthyroidism when extra iodine is ingested.

Thyroid function after hysterosalpingography using an oil-soluble iodinated contrast medium. In individuals with a normal thyroid, the gland eventually escapes from this inhibitory effect and iodide organification resumes; however, in patients with underlying autoimmune thyroid disease, the suppressive action of high iodide may persist.

Se continuar a navegar, consideramos que aceita o seu uso. The risk of CHD mortality and atrial fibrillation but not other outcomes in subclinical jos is higher among patients with very low levels of thyrotropin.

Comprehensive Handbook of Iodine: Are you a health professional able to prescribe or dispense drugs? Thyroid hormones upregulate the expression of the sarcoplasmic reticulum calcium-activated ATPase and downregulate the expression of phospholamban. SRJ is a prestige metric based on the idea that not all citations are the same. This page was last edited on 7 Augustat Both hypothyroidism and hyperthyroidism increase the risk of coronary artery efecfo, left cardiomyopathy, electrophysiological abnormalities, and all-cause mortality.

In both instances, the underlying cause is the high concentration of iodine in this medication.

Wolff–Chaikoff effect – Wikipedia

Iodine-induced hyper-thyroidism after contrast media. Med J Aust ; 4: Subclinical thyroid dysfunction is relatively common in patients over 65 years of age.

Dorland’s Illustrated Medical Dictionary. Subclinical thyroid dysfunctions are independent risk factors for mortality in a 7. The Jod-Basedow effect also Jod-Basedow syndrome and Jod-Basedow phenomenon is hyperthyroidism following administration of iodine or iodide, [1] either as a baeedow supplement or as contrast medium.


Disfunci tiroidea posexposici a medio de contraste yodado. Cardiovascular and hemodynamic changes in a hypothyroid state. Neuroendocrinology Pediatric endocrinology Psychoneuroendocrinology Reproductive endocrinology and infertility. Previous article Next article.

Acad Radiol ;5 6: Effect of iodinated contrast media on thyroid function in adults. From Monday to Friday from 9 a. Eur Radiol ;14 5: Hyperthyroid subjects given iodide may experience a decrease in basal metabolic rate that is comparable to that seen after thyroidectomy.

Hospital Departamental Santa Sof de Caldas. Views Read Edit View history. Iodide induced hyperthyroidism with computed tomography contrast fluids. Hyperthyreoserisiko bei Kontrastmittelun- tersuchungen.

Wolff–Chaikoff effect

Hypothalamic—pituitary—thyroid axis Hypothalamic—pituitary—adrenal axis Hypothalamic—pituitary—gonadal axis Hypothalamic—pituitary—somatotropic axis Hypothalamic—pituitary—prolactin axis Hypothalamic—neurohypophyseal system Renin—angiotensin system. Views Read Eefcto View history. Mico Endocrinogo de la Clica Comfamiliar Risaralda.

Iodine and thyroid disease. Acta radiol ;54 1: Prevalence of thyroid dysfunction and effect of contrast medium on thyroid metabolism in cardiac patients undergoing coronary angiography. The Wolff—Chaikoff effect is also jor of the mechanism for the use of potassium iodide in nuclear emergencies.

Print Send to baedow friend Export reference Mendeley Statistics. Br J Radiol ;54 SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.

Fortschr Geb Rontgenstrahlen Nuklearmed Ergan- zugsbd ; Larry Jameson, Anthony s.